Anthony Vernon
anthony.vernon@kcl.ac.uk
VernonLab_KCL
Website
Research Interests
Theme 1: Linking neuroimaging data to molecular and cellular phenotypes: Linking macroscale neuroimaging signals measured from individuals with psychiatric and neurological disorders to microscale mechanisms to advance knowledge of causative biological pathways. USP: Linking clinical PET data to cellular form and function at the individual level using patientderived hiPSC models
Theme 2: Neuro-immune interactions Using microglia and neurons differentiated from human induced pluripotent stem cells (hiPSC), we seek to understand how genetic and environmental risk for psychiatric and neurological disorders impacts on neuroimmue interactions such as synapse formation and elimination
Most significant discovery
Human neuroimaging studies in psychiatric disorders cannot readily separate illness from
putative iatrogenic effects of psychotropic medications. Using a cross-species imaging
approach we have provided in vivo evidence for reduced synaptic density in schizophrenia
which is unlikely to be affected by antipsychotic drugs.
Educational Interests
• Joint-lead: MRC PhD program Neurodevelopmental Disorders
• Module lead – Neurodevelopmental Disorders: From Bench to
Bedside (Distance Learning)
• Teaching – BSc. Neuroscience and Psychology, Biomedical
Sciences, Neuroscience, MBBS; MSc. Neuroscience, Clinical
Neuroscience, Psychiatric research, Clinical Neuropsychology,
Biological Foundations of Mental Health (Distance Learning)
Top 4 Publications
Methods / Expertise
hiPsc
MRI/PET
Neuro-immune interactions