Antonio Valentin

Antonio.valentin@kcl.ac.uk

KCLMesCobraD

Website

Research Interests

My actual research interest is mainly based on techniques using neuromodulation for diagnosis and treatment of patients with refractory epilepsy. I am presently working on potential treatments for this condition, including deep brain stimulation (DBS) with a UK study for the treatment of children with Lennox Gastaut Syndrome (LifeArc 2021 grant). I am also involved in the development of new wireless intracranial neuromonitoring devices for epileptic patients (NIHR i4i 2022 grant). Another aspect of my research interest is based on the development of a new artificial intelligence system for the assessment and management of complex brain disorders, including epilepsy, sleep, and dementia (EU Horizon2020 grant).

Most significant discovery

At KCL/KCH, I developed the technique of single-pulse electrical stimulation (SPES) for
patients with intracranial recordings, a standard diagnostic test used around the world. I
have also been involved in deep brain stimulation (DBS) for epilepsy. At present, I am
collaborating with other UK groups in the development of new DBS devices.

Educational Interests

• Co-director in the ILAE VIREPA EEG Advanced course The role of EEG in the Diagnosis and
Management of Epilepsy
• Organisational role in the Laboratory Research Project in Neuroscience (6BBYN306)

Top 4 Publications

• Stavropoulos et al, Brain Stimul. 2021 MarApr;14(2):226-229
• Valentin et al, Eur J Paediatr Neurol. 2017 Jan;21(1):223-231
• Valentin et al, Epilepsia. 2013 Oct;54(10):1823-33
• Valentin et al, Lancet Neurol. 2005 Nov;4(11):718-2

Methods / Expertise

• Intracranial recordings epilepsy
• Deep Brain Stimulation (DBS)
• Transcranial Magnetic stimulation (TMS) and EEG