
Brenda Williams
Research Interests
Most significant discovery
• Neurons and oligodendrocytes are derived from a common progenitor cell
(Williams et al., 1991)
• Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis
(Parviainen et al., 2017).
Educational Interests
• Curriculum design and development
• Neuroeducation
• Inclusive and diverse assessment and feedback practices
• Closing the attainment gap
• Supporting student success and wellbeing
Top 4 Publications
Williams et al. The generation of neurons and oligodendrocytes from a common precursor cell. Neuron, 1091. https://doi.org/ 10.1016/0896-6273(91)90381-9
Anderson GW, et al. Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16. Stem Cell Res, 2015. https:// doi.org/10.1186/ s13287-015-01368
Michelucci A, et al. The Neurogenic Potential of Astrocytes Is Regulated by Inflammatory Signals. Mol Neurobiol, 2016. https://doi.org/ 10.1007/s12035-015-9296-x
Parviainen L, et al. Glial cells from Juvenile Batten disease mice are functionally impaired and detrimental to neurons. Acta neuropathol commun , 2017. https://doi.org/10.1186/ s40478-017-0476-y
Methods / Expertise
• Neural stem cells
• Cellular models
• Neuron-glial interactions
