Joseph Bateman

Research Interests

Cellular signalling pathways are molecular connections that control development and function in nerve cells. Changes in signalling pathways alter the molecular wiring in nerve cells and cause a wide range of neurological diseases, ranging from neurodevelopmental disorders to neurodegenerative diseases. Many neurological disorders are poorly understood and lack effective treatments. We aim to uncover the molecular mechanisms contributing to these diseases by studying how changes in signalling pathways, such as motor and mitochondrial signalling, alter nerve cell development and function. Our research will contribute to improved understanding and the development of novel treatments for currently intractable neurological disorders.

Most significant discovery

Demonstration that mTOR signalling regulates neurogenesis and the discovery of novel mTOR substrates that regulate neurogenesis.

Educational Interests

• Models of human disease
• Small group teaching
• Integrating research and teaching

Top 4 Publications

Methods / Expertise

• Drosophila models
• Transcriptomics/metabolomics
• Signalling