Mark Richardson

Research Interests

The Richardson Lab is a multidisciplinary team focused on human epilepsy, one of the commonest conditions affecting brain health. Epileptic seizures can be devastating, interrupting normal life, and leading to serious injury and even death. We seek to understand why an epileptic seizure starts now; why did the seizure emerge at this time, rather than 6 hours ago, or tomorrow? We tackle this question with two main approaches: (1) using data obtained from people with epilepsy and healthy controls, such as EEG, DTI, and fMRI, we construct dynamic models to investigate the conditions required for a seizure to emerge; and (2) using remote sensor technology, study the patterns of occurrence of seizures over very long periods of time in people with epilepsy, to create seizure forecasting systems.

Most significant discovery

Twenty years ago, the Richardson Lab was one of the first groups to describe epilepsy as a dynamic brain network disorder, and to build a formal conceptual framework around this, called Brain Network Ictogenicity. Over the last decade, we have become a globallyleading centre in using remote sensor technology to create seizure detection and forecasting systems, and to move these ideas into clinical practise.

Educational Interests

• Clinical epilepsy and related
disorders
• Multidisciplinary lab projects,
combining neuroscience,
engineering and clinical relevance

Top 4 Publications

Methods / Expertise

• EEG
• TMS
• Remote sensor monitoring
• MRI